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In this article, we will provide some information related to research from a collaboration between the University of Kansas Cancer Center, California State University San Marcos, and Brown University. Researchers conducted a randomized trial to compare the presence of certain biomarkers in vaping versus smoking.

The study, titled "The Effects of Pod-style E-cigarettes vs. Cigarettes on Carcinogen Exposure Among African American and Latinx Smokers," consisted of a six-week randomized trial comparing e-cigarette use with traditional cigarette use, among African American and Latinx smokers.

The KU Cancer Center's Cancer Prevention and Control research program co-program leader, Nikki Nollen, PhD, served as the principal investigator for the site.

“Fourth-generation e-cigarettes contain high concentrations of nicotine and other attractive features that may support switching and reduce potential health risks among those who smoke combustible cigarettes,” said Dr. Nollen. "We wanted to examine biomarkers of exposure in both groups and determine the risk-benefit trade-offs of e-cigarettes."

Participants were adult smokers who consumed at least 5 cigarettes/day for at least 25 of the past 30 days for at least 6 months and were interested in switching to electronic cigarettes. Data was analyzed and collected between September 18, 2019, and September 4, 2020.

According to the research Abstract, study subjects were offered a 6-week supply of vaping products in their preferred flavor (at 5% nicotine) along with brief education, training, and action planning to fully switch to e-cigarettes from combustible cigarettes. The control group, meanwhile, was instructed to continue smoking as usual.

Decrease in analyzed biomarkers measured

The collected data showed a reduction in the analyzed biomarkers. “The primary outcome was a decrease in urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) concentration at week 6. Secondary outcomes were changes in urinary cotinine, expired carbon monoxide (CO), respiratory symptoms, lung function, blood pressure, combustible cigarette consumption over the past 7 days, and switching rates (e-cigarette group only) at weeks 2 and 6.”

Nollen pointed out that the degree of reduction in certain biomarkers was quite surprising. “What was most surprising was the magnitude of change experienced by those in the e-cigarette group,” said Dr. Nollen. "They reduced their NNAL by 64%, carbon monoxide by 47% and respiratory symptoms by 37% compared to the control group who continued smoking as usual."

Dual users also felt the benefits

Furthermore, the study reported that benefits were experienced not only by those who switched completely but also by dual users, although to a lesser extent than those who switched completely. “The e-cigarette trajectory subgroups differed significantly for NNAL and CO levels. Exclusive e-cigarette users experienced the largest changes, followed by dual users, and then exclusive cigarette smokers. At week 6, exclusive e-cigarette users had a significantly greater reduction in NNAL and CO levels than dual users and smokers. Dual users also experienced a greater decrease in CO levels compared to exclusive smokers.”

So, that concludes this short article. Hopefully, an article like this can provide new insights for you vapers. Of course, if you want to share and gain more knowledge about vape, you can visit your nearest Vapeboss retail store, where our Vaporista will assist you and provide a lot of information about the world of vape. Also, if you need vape supplies and have difficulty buying them due to rainy conditions, you can contact our retail WA for purchases with a COD system. Because Vapeboss is the most complete and trusted vape store since 2014, any vape needs you have will definitely be available there.

Keep Calm and Vape Like a Boss and Always stay safe while vaping and always adhere to health protocols during the current pandemic. Have a nice day Bigboss!